Die chronologische Liste zeigt aktuelle Veröffentlichungen aus dem Forschungsbetrieb der Hochschule Weihenstephan-Triesdorf. Zuständig ist das Zentrum für Forschung und Wissenstransfer (ZFW).
Prof. Dr. Dominik Grimm,
Damian Roqueiro,
Patrice A. Salomé,
Stefan Kleeberger,
Bastian Greshake,
Wangsheng Zhu,
Chang Liu,
Christoph Lippert,
Oliver Stegle,
Bernhard Schölkopf,
Detlef Weigel,
Karsten Borgwardt
Berechtigungen: Open Access
Berechtigungen: Peer Reviewed
easyGWAS: A Cloud-Based Platform for Comparing the Results of Genome-Wide Association Studies (2017) The Plant Cell 29 (1).
DOI: 10.1105/tpc.16.00551
The ever-growing availability of high-quality genotypes for a multitude of species has enabled researchers to explore the underlying genetic architecture of complex phenotypes at an unprecedented level of detail using genome-wide association studies (GWAS). The systematic comparison of results obtained from GWAS of different traits opens up new possibilities, including the analysis of pleiotropic effects. Other advantages that result from the integration of multiple GWAS are the ability to replicate GWAS signals and to increase statistical power to detect such signals through meta-analyses. In order to facilitate the simple comparison of GWAS results, we present easyGWAS, a powerful, species-independent online resource for computing, storing, sharing, annotating, and comparing GWAS. The easyGWAS tool supports multiple species, the uploading of private genotype data and summary statistics of existing GWAS, as well as advanced methods for comparing GWAS results across different experiments and data sets in an interactive and user-friendly interface. easyGWAS is also a public data repository for GWAS data and summary statistics and already includes published data and results from several major GWAS. We demonstrate the potential of easyGWAS with a case study of the model organism Arabidopsis thaliana, using flowering and growth-related traits.
Ümit Seren,
Prof. Dr. Dominik Grimm,
Joffrey Fitz,
Detlef Weigel,
Magnus Nordborg,
Karsten Borgwardt,
Arthur Korte
Berechtigungen: Open Access
Berechtigungen: Peer Reviewed
AraPheno: a public database for Arabidopsis thaliana phenotypes (2017) Nucleic Acids Research 45 (D1), S. D1054-D1059.
DOI: 10.1093/nar/gkw986
Seymour Danelle,
Eunyoung Chae,
Prof. Dr. Dominik Grimm,
Carmen Martin Pizarro,
Anette Habring-Müller,
Francois Vasseur,
Barbara Rakitsch,
Karsten Borgwardt,
Daniel Koenig,
Detlef Weigel
Berechtigungen: Open Access
Berechtigungen: Peer Reviewed
Genetic architecture of nonadditive inheritance in Arabidopsis thaliana hybrids (2016) Proceedings of the National Academy of Sciences (PNAS) 113 (46), S. E7317-E7326.
DOI: 10.1073/pnas.1615268113
Angela McGaughran,
Christian Rödelsperger,
Prof. Dr. Dominik Grimm,
Jan M. Meyer,
Eduardo Moreno,
Katy Morgan,
Mark Leaver,
Vahan Serobyan,
Barbara Rakitsch,
Karsten Borgwardt,
Ralf J. Sommer
Berechtigungen: Open Access
Berechtigungen: Peer Reviewed
Genomic profiles of diversification and genotype-phenotype association in island nematode lineages (2016) Molecular Biology and Evolution 33 (9), S. 2257-2272.
DOI: 10.1093/molbev/msw093
T Kawakatsu,
. ..,
Prof. Dr. Dominik Grimm,
. ..,
Joseph R Ecker
Berechtigungen: Peer Reviewed
Epigenomic Diversity in a Global Collection of Arabidopsis thaliana Accessions (2016) Cell 166 (2), S. 492-505.
DOI: 10.1016/j.cell.2016.06.044
C Alonso-Blanco,
. ..,
Prof. Dr. Dominik Grimm,
. ..,
Detlef Weigel,
X Zhou
Berechtigungen: Open Access
Berechtigungen: Peer Reviewed
1,135 Genomes Reveal the Global Pattern of Polymorphism in Arabidopsis thaliana (2016) Cell 166 (2), S. 481-491.
DOI: 10.1016/j.cell.2016.05.063
Prof. Dr. Dominik Grimm
easyGWAS: An Integrated Computational Framework for Advanced Genome-Wide Association Studies (2015) Universitätsbibliothek Tübingen .
Federica Eduati,
Lara M Mangravite,
. ..,
Prof. Dr. Dominik Grimm,
. ..,
Julio Saez-Rodriguez
Berechtigungen: Open Access
Berechtigungen: Peer Reviewed
Prediction of human population responses to toxic compounds by a collaborative competition (2015) Nature Biotechnology 33 , S. 933-940.
DOI: 10.1038/nbt.3299
Betreuung der Publikationsseiten
Gerhard Radlmayr
Referent für Wissenstransfer und Forschungskommunikation
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